Regenerative Medicine

PRP | nSTRIDE® APS

Advanced Injection for Knee Osteoarthritis

Available at these clinics:

Oakville

About the service

nSTRIDE® APS (Autologous Protein Solution) is an advanced biologic Platelet Rich Plasma injection for osteoarthritis of the knee that uses a concentrated solution from your own blood to target joint inflammation, pain and degeneration. Rich in anti-inflammatory proteins, IL-1 receptor antagonist (IL-1ra), growth factors, platelets, and anti-catabolic proteins.

nSTRIDE® is injected directly into the knee under real-time ultrasound guidance for precise treatment. Unlike steroids or lubricating injections, nSTRIDE is designed to interrupt the inflammatory cascade, support joint health, improve mobility, and help protect cartilage from further breakdown.

✅ Ultrasound Guidance

  • Precise joint-space targeting
  • Accurate delivery of the solution
  • Improved safety and reduced risk of misplacement
  • X-ray imaging is used to confirm osteoarthritis and joint anatomy prior to treatment.

✅ Benefits of nSTRIDE® APS

  • Long-lasting pain relief (often up to 12 months or more)
  • Improved mobility and daily function
  • A targeted approach that addresses inflammation at the molecular level
  • A single, image-guided injection (non-surgical and autologous)

✅ Ideal Candidate

  • Have mild to moderate knee osteoarthritis
  • Want to avoid surgery or frequent steroid injections
  • Have had limited response to treatments like corticosteroids, or hyaluronic acid
  • Want a biologic option using your own blood

1. Assessment + Ultrasound Imaging

  • We initiate a focused knee exam, followed by review of any diagnostics to assess joint structure and osteoarthritis severity
  • If needed, additional X-ray, ultrasound, or MRI imaging may be recommended to assess disease stage, joint alignment, and other factors that may influence treatment outcomes

2. In-clinic Procedure

  • Blood draw, A small blood sample is taken from your arm
  • On-Site Processing, Your blood is processed on-site to prepare the APS solution
  • Ultrasound-Guided, injected precisely into the knee joint

3. Post Treatment

  • Most clients return to light activity within 24–48 hours.
  • A personalized rehab plan is provided based on your goals and symptoms

✅ Results Timeline

  • Some patients report improvement within 2–4 weeks
  • Peak effects are often seen around 2–3 months
  • Many clients experience meaningful relief for up to 12 months, depending on severity of osteoarthritis, activity demands and overall joint health

✅ Pricing 💳

  • nSTRIDE® APS Injection +
  • Ultrasound-guided   $1290
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Frequently Asked Questions

Is the injection painful?

Most patients tolerate the procedure well. Local anesthetic may be used, and ultrasound guidance supports comfort and precision.

Will I need more than one injection?

nSTRIDE is designed as a single-injection treatment, but some patients may benefit from re-evaluation if symptoms return (often around the 12-month mark).

When can I return to normal activity?

Most patients resume light activity quickly, with a personalized rehab timeline based on your specific injury and treatment area.

Is this backed by research?

APS has been studied for early to moderate knee OA and has shown symptom improvement with a favorable safety profile in published clinical research.

Is nSTRIDE covered by OHIP or insurance?

nSTRIDE is not covered by OHIP. Some extended health plans may reimburse a portion depending on your plan.