Regenerative Medicine

nSTRIDE® APS Injection Therapy

Advanced injection therapy for knee osteoarthritis relief.

Available at these clinics:

Mississauga

Oakville

About the service

🦵 Advanced Anti-Inflammatory Joint Support for Knee Osteoarthritis

At MedCAiRE Health, we proudly offer nSTRIDE® APS (Autologous Protein Solution)—a cutting-edge injectable treatment designed to relieve knee osteoarthritis pain by reducing inflammation at its biological source. Using a Zimmer Biomet centrifuge and guided by real-time ultrasound, this single-injection solution offers long-lasting relief and cartilage protection.

❓ What Is nSTRIDE® APS?

nSTRIDE is an autologous biologic therapy that concentrates powerful anti-inflammatory proteins and growth factors from your own blood. These proteins are processed into a solution that is injected directly into your knee joint—using ultrasound guidance for maximum accuracy.

nSTRIDE contains:

  • IL-1 receptor antagonists (IL-1ra) to block key inflammatory pathways
  • Growth factors to support joint repair
  • Anti-catabolic proteins to slow joint breakdown

⚠️ nSTRIDE is not a steroid or lubricant, but a biologically targeted solution aimed at interrupting the inflammatory cascade that causes cartilage deterioration in knee osteoarthritis.

🖥️ Why Ultrasound Guidance Matters

At MedCAiRE, all nSTRIDE injections are performed under ultrasound guidance to ensure:

  • Precise joint space targeting
  • Optimal solution delivery
  • Increased safety and reduced risk of misplacement
  • Better patient outcomes

📸 X-ray imaging also helps us confirm osteoarthritis severity and joint anatomy before proceeding.

🌟 Benefits of nSTRIDE® APS Therapy

✔️ Long-lasting pain relief (6–12 months or more)
✔️ Improved joint function and daily mobility
✔️ Targets inflammation at the molecular level
✔️ Single, ultrasound-guided injection
✔️ Non-surgical, natural, and autologous (from your own blood)

🩺 Procedure Overview

1. Initial Consultation + Diagnostic Ultrasound

A detailed evaluation of your knee is performed, including an ultrasound exam to assess joint structure and OA severity.

2. Blood Draw & Processing

A small blood sample is processed in our on-site Zimmer Biomet centrifuge to create the autologous protein solution (APS).

3. Ultrasound-Guided Injection

The APS is precisely injected into your knee joint under real-time ultrasound guidance, ensuring proper delivery.

4. Post-Care Instructions

You may resume light activity within 24–48 hours. A personalized rehab plan may be provided.

💵 Pricing

💲 nSTRIDE® APS Single Injection (Ultrasound-Guided): $1245 CAD
(Includes Zimmer Biomet processing, diagnostic ultrasound, ultrasound-guided injection, and follow-up care.)

👥 Ideal Candidates

You may benefit from nSTRIDE if you:

  • Have mild to moderate knee osteoarthritis
  • Want to avoid surgery or steroid use
  • Have not responded to other therapies like PRP, corticosteroids, or hyaluronic acid
  • Are looking for a biological solution with lasting relief

📚 Clinical Backing

nSTRIDE has been studied in multiple international clinical trials and has shown:

  • Significant improvement in pain, stiffness, and physical function
  • A favorable safety profile with long-lasting effects up to 12 months
  • Reduction of key inflammatory markers like IL-1 and TNF-α
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Frequently Asked Questions

Is the injection painful?

Most patients tolerate the procedure well. We use local anesthetic and ultrasound guidance to ensure comfort and precision.

Will I need more than one injection?

nSTRIDE is designed as a single-injection treatment. Some patients may benefit from re-evaluation after 12 months if symptoms return.

Is this covered by insurance?

nSTRIDE is not covered under OHIP. Some extended health plans may provide partial reimbursement—please inquire with your provider.

How soon will I notice results?

Some patients notice improvement within 2–4 weeks. Peak effects are typically seen within 2–3 months.

Why Choose MedCAiRE?

  • Experienced team using Zimmer Biomet-approved centrifuge
  • Diagnostic ultrasound and image-guided injection technique
  • Transparent pricing: $1245 CAD per injection
  • Focused on regenerative, non-surgical joint care